Step-Up to the Bedside is now in its updated 2nd edition. Grounded in the basic sciences, this text is one of the few complete cased based review books for the USMLE Step 1. The material is presented around a classic patient presentation of a common clinical condition (approzimately 100 case studies, onlne and in print) and the findings leading to the correct diagnosis, folowed by discussion of the related basic science concepts.  In addition to providing excellent Step 1 preparation, Step-Up to the Bedside is also the ideal bridge between the pre-clinical years and the clinical years.