For the past two decades, with more than 85,000 copies sold,
Designing Clinical Research has set the standard as a practical guide to planning and implementing clinical research. This Third Edition retains the concise, easy-to-read approach of the earlier editions, is full of updated examples, and adds new developments in the methods of clinical and translational research.
• The research question • Sample size and power
• Study subjects • Community and international research
• Measurements and questionnaires • Research using existing data
• Observational study designs • Ethical issues
• Medical test studies • Data management and quality control
• Clinical trials • Getting funded
This book avoids statistical notation and; concentrates on strategies for tackling the many difficult judgments involved in designing a study. The result is a sophisticated and practical understanding of what clinical research is all about — finding a good research question and planning an efficient, effective and ethical design.
The authors are seasoned clinical investigators who have guided more than 2,000 physicians and health professionals in their efforts to design a study. The authors bring to the task of writing this text not only vast experience, but love of the material and enthusiasm for teaching it.